Ginkgo Biloba - In 2004, researchers at Stanford University discovered the main culprit. GABA receptors, which mediate inhibition in the brain, are over-active in a mouse model of Down syndrome. This means the receptors are ON continuously in individuals with Down syndrome. (Supporting Study) The result was- it did not allow the nerves in the memory and learning area of the brain to fire. In other words, the nerves were shut down. To compensate for increased activity of the GABA receptor, a GABA antagonist was used to turn it down. (Supporting Study) Ginkgo Biloba is a GABA antagonist which has been used for over 4000 years (Supporting Study).
Prozac - The University Of Maryland School Of Medicine treated Down syndrome miceŁ with prozac for 24 days (2006). It increased neurogenesis (the formation of new nerves) to a normal level (Supporting Study). This is like increasing the hardware on your computer. It allows you to run more complicated software. In fetuses with Down syndrome, neurons fail to show normal dendritic development, yielding a "tree in winter" appearance. This developmental failure is thought to result in mental retardation (Supporting Study)
Focalin XR is an ADHD medicine that increases focus and decreases impulsiveness and hyperactivity. It is a mild stimulant. As our children improved, we became increasingly aware of their inability to attend to the tasks at hand. (Some doctors prescribe Concerta, Vivance or Ritalin instead)
Phosphatidylcholine is a phospholipid that makes up 50% of the cell membrane. The membrane is the lining of every nerve cell that carries our signals. We are trying to heal the brain by growing new neurons and allowing them to fire. Giving PC is like bringing the bricks to the construction site when building a house. (View details)
Formulated with a 4:1 Ratio of Omega 6 to Omega 3 in Liquid form or Softgel pills.
Of the tens of thousands of molecules that make up the life of a cell, Phosphatidylcholine (PC) stands apart; probably the most important one of all. BodyBio PC is made of only pure phospholipids which automatically form liposomes in the watery environment of the body, but it goes one important step further....it is also formulated with the essential lipids at a 4:1 ratio. Most PC currently available has an EFA ratio of ~12:1. BodyBio PC not only has a higher concentration of PC, up to 66% but also maintains EFA concentration at the preferred 4:1 ratio, a BodyBio exclusive.
Body Bio Balanced Oil
Body Bio Balanced Oil is included to reduce inflammation so that we reduce the onset of Alzheimer's Disease. It was shown in 2004 that reducing inflammation in the brain of the DS mouse prevented neuron loss and delayed decline of function.
B12 and Folinic Acid
Studies have shown that there is a tendancy in Down syndrome to have low levels of B12 and Folinic Acid. Replacing B12 and Folinic Acid helps to normalize metabolism. Low levels of vitamin B12 and Folinic Acid have also been linked to Alzheimer's Disease. (Folinic Acid is a more active form of Folic Acid)
CMF Founder's Statement:
"I was asked to come up with a statement for the website that says something to the effect that all people with Down syndrome are not the same. And, I totally agree that they are not clones. But at the same time, we who love someone with DS are lucky that there are so many similarities of the DS symptoms. This makes it possible to come up with effective treatments. Down syndrome is a constellation of symptoms which means there is a long list of observed similarities. This does not mean that every individual gets every symptom. However, there is one symptom that is universal; that symptom is unfortunately, mental retardation (you may call it developmental delays or the next contortion of language - intellectual disabilities). In my world view, what you call it does not change my son’s reality. I put together the website to give parents information that I could see was being lost in the annals of research papers. What someone does with that information, is up to them. There is no pressure on the website. I don’t make any profit from the items on the protocol and I don't sell or have anything to do with the sale of any of them. I just want parents to know what has been discovered and what is currently being researched. My mission is simply to help other parents by sharing information."
Teresa Cody, DDS