Phosphatidylcholine

Efficacy of vitamin E, phosphatidyl choline and pyruvate on Abeta neurotoxicity in culture.

Shea TB, Ekinci FJ, Ortiz D, Wilson TO, Nicolosi RJ.

J Nutr Health Aging. 2003;7(4):252-5.

PMID: 12917750 [PubMed - indexed for MEDLINE]

Cholinergic precursors in the treatment of cognitive impairment of vascular origin: ineffective approaches or need for re-evaluation?

Parnetti L, Mignini F, Tomassoni D, Traini E, Amenta F.

J Neurol Sci. 2007 Jun 15;257(1-2):264-9. Epub 2007 Feb 28. Review.

PMID: 17331541 [PubMed - indexed for MEDLINE]

Cognitive improvement in mild to moderate Alzheimer's dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial.

De Jesus Moreno Moreno M.

Clin Ther. 2003 Jan;25(1):178-93.

PMID: 12637119 [PubMed - indexed for MEDLINE]

Acceleration of phosphatidylcholine synthesis and breakdown by inhibitors of mitochondrial function in neuronal cells: a model of the membrane defect of Alzheimer's disease.

Farber SA, Slack BE, Blusztajn JK.

FASEB J. 2000 Nov;14(14):2198-206.

PMID: 11053240 [PubMed - indexed for MEDLINE]

Evidence for a membrane defect in Alzheimer disease brain.

Nitsch RM, Blusztajn JK, Pittas AG, Slack BE, Growdon JH, Wurtman RJ.

Proc Natl Acad Sci U S A. 1992 Mar 1;89(5):1671-5.

PMID: 1311847 [PubMed - indexed for MEDLINE]

Alterations of phospholipid metabolites in postmortem brain from patients with Alzheimer's disease.

Nitsch R, Pittas A, Blusztajn JK, Slack BE, Growdon JH, Wurtman RJ.

Ann N Y Acad Sci. 1991;640:110-3.

PMID: 1663712 [PubMed - indexed for MEDLINE]

Cognitive impairment in folate-deficient rats corresponds to depleted brain phosphatidylcholine and is prevented by dietary methionine without lowering plasma homocysteine.

Troen AM, Chao WH, Crivello NA, D'Anci KE, Shukitt-Hale B, Smith DE, Selhub J, Rosenberg IH.

J Nutr. 2008 Dec;138(12):2502-9.

PMID: 19022979 [PubMed - indexed for MEDLINE]

Cholinomimetic agents and neurocognitive impairment following head injury: a systematic review.

Poole NA, Agrawal N.

Brain Inj. 2008 Jul;22(7-8):519-34. Review.

PMID: 18568705 [PubMed - indexed for MEDLINE]

Efficacy of vitamin E, phosphatidyl choline, and pyruvate on buffering neuronal degeneration and oxidative stress in cultured cortical neurons and in central nervous tissue of apolipoprotein E-deficient mice.

Shea TB, Ekinci FJ, Ortiz D, Dawn-Linsley M, Wilson TO, Nicolosi RJ.

Free Radic Biol Med. 2002 Jul 15;33(2):276-82.

PMID: 12106823 [PubMed - indexed for MEDLINE]

10:

The neurobiological effects of colchicine: modulation by nerve growth factor.

Barone S Jr, Bonner M, Tandon P, McGinty JF, Tilson HA.

Brain Res Bull. 1992 Feb;28(2):265-74.

PMID: 1596747 [PubMed - indexed for MEDLINE]

11:

Efficacy of vitamin E, phosphatidyl choline and pyruvate on Abeta neurotoxicity in culture.

Shea TB, Ekinci FJ, Ortiz D, Wilson TO, Nicolosi RJ.

J Nutr Health Aging. 2003;7(4):252-5.

PMID: 12917750 [PubMed - indexed for MEDLINE]

12:

Essential fatty acids and their metabolites could function as endogenous HMG-CoA reductase and ACE enzyme inhibitors, anti-arrhythmic, anti-hypertensive, anti-atherosclerotic, anti-inflammatory, cytoprotective, and cardioprotective molecules.

Das UN.

Lipids Health Dis. 2008 Oct 15;7:37. Review.

PMID: 18922179 [PubMed - indexed for MEDLINE]

13:

Folic acid with or without vitamin B12 for the prevention and treatment of healthy elderly and demented people.

Malouf R, Grimley Evans J.

Cochrane Database Syst Rev. 2008 Oct 8;(4):CD004514. Review.

PMID: 18843658 [PubMed - indexed for MEDLINE]

14:

Folate deprivation, the methionine cycle, and Alzheimer's disease.

Tchantchou F, Shea TB.

Vitam Horm. 2008;79:83-97.

PMID: 18804692 [PubMed - indexed for MEDLINE]